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Title: Magnesium bioavailability from mineral water. A study in adult men

Author: Verhas M.[1], de La Guéronnière V.[2], Grognet J-M.[3], Paternot J.[1], Hermanne A.[4], Van den Winkel P.[4], Gheldof R.[1], Martin P.[1], Fantino M.[5], Rayssiguier Y.[6], Correspondence: M Verhas*

[1]CHU Brugmann-Free University of Brussels, Brussels, Belgium,
[2]SEV, 92340 Bourg la Reine, France,
[3]Departement des Sciences du Vivant, CEA, Gif sur Yvette, France,
[4]Cyclotron Eenheid-Vrije Universiteit Brussels, Brussels, Belgium,
[5]Laboratoire de Physiologie CHU Dijon, Dijon, France,
[6]Laboratoire de Physiologie, INRA, Clermont-Ferrand-Theix, France,
[*]Department of Nuclear Medicine, Brugmann Hospital, Free University of Brussels, 4 Place Van Gehuchten, 1020, Brussels, Belgium. E-mail:

Journal: European Journal of Clinical Nutrition, May 2002, vol. 56, no. 5 pp. 442-447


Objective: To assess magnesium enteral absorption from a magnesium-rich mineral water.

Design: Experimental study.

Setting: Department of Nuclear Medicine, Brugmann Hospital, Brussels, Belgium.

Subjects: Ten healthy male volunteers in the age range 25–42 y.

Intervention: Each subject completed two sessions in a random order. At one session, they received an oral load of 300 ml of water (containing 1.2 mmol Mg), traced with 28Mg, and at the other session they received an intravenous injection of 28Mg, in order to take into account the metabolism of endogenous magnesium. The dietary consumption was further noted on a weekly diary.

Results: The mean bioavailability was 59.1% (s.d.±13.6). Magnesium absorption and age were significantly inversely correlated (r=-0.68, P=0.035).

Conclusion: Magnesium-rich mineral water is a reliable source of magnesium. Our observation of decreased magnesium absorption with age deserves further investigations.

Sponsorship: The study was sponsored by SEV, Bourg la Reine, France.

European Journal of Clinical Nutrition (2002) 56, 442–447.

This page was uploaded on September 22, 2004